All You Need To Know About Muscular Dystrophy
Stem Cell Therapy For Muscular Dystrophy
Muscular dystrophies (MD) are a category of hereditary genetic diseases that cause muscles to deteriorate over time, resulting in increasing disability.
MD is a progressive disease, meaning it worsens over time. It usually starts with a small set of muscles before spreading to the rest of the body.
Some forms of MD eventually impair the heart or breathing muscles, causing the condition to become life-threatening.
Although there is no cure for MD, medication can help with many of the symptoms.
Causes Of Muscular Dystrophy
Changes (mutations) in the genes that control the structure and function of a person's muscles cause MD.
The mutations induce alterations in muscle fibres that make it difficult for the muscles to operate properly. This results in growing disability over time.
Mutations are frequently passed down from one's parents. If you have a family history of MD, your doctor may recommend genetic testing and counselling to determine your risk of acquiring the disease or having a child with MD, as well as to discuss your treatment choices.
Types Of Muscular Dystrophy
There are numerous varieties of MD, each with its own set of symptoms. Not all types result in severe disability, and many have no impact on life expectancy.
The following are some of the more frequent kinds of MD:
Duchenne MD is one of the most prevalent and severe types of the disease, affecting boys in their early childhood and causing them to live barely into their 20s or 30s.
Myotonic dystrophy is a type of MD that can strike at any age; life expectancy isn't necessarily impacted, but persons with a severe version of the disease may live shorter lifetimes.
Facioscapulohumeral MD is a kind of MD that can develop in childhood or adulthood, and it normally advances slowly and isn't life-threatening.
Becker MD is similar to Duchenne MD, although it manifests later in childhood and is less severe; life expectancy is largely unaffected.
limb-girdle MD — a group of illnesses that typically manifest themselves in late childhood or early adulthood; some types can proceed swiftly and be life-threatening, while others take longer to manifest.
Oculopharyngeal MD - a type of MD that normally doesn't manifest until a person is between the ages of 50 and 60, and doesn't have a significant impact on life expectancy.
Emery-Dreifuss MD — a kind of MD that begins in childhood or early adulthood and affects the majority of persons until they reach middle life.
Muscle Dystrophy Diagnosis
The various kinds of MD can be diagnosed using a variety of approaches. Depending on when symptoms first show, the age at which the illness is identified varies.
Some or all of the following phases will be involved in the diagnosis:
- looking into any symptoms
- Any family history of MD should be discussed.
- inspection of the body
- tests on the blood
- Nerve and muscle tests with electricity
- a biopsy of the muscle (where a small tissue sample is removed for testing)
If you or your child exhibits any symptoms of MD, see your physician. They may refer you to a hospital for more tests if necessary.
How It Is Treated?
Although there is no cure for MD, there are a number of therapies that can help with the physical limitations and issues that may arise. These can include the following:
Mobility Help — Exercise, physiotherapy, and physical aids
Support groups — to help people cope with the practical and emotional effects of MD.
Scoliosis is a type of postural deformity that requires surgery to rectify.
Medication – such as steroid injections to increase muscle mass or ACE inhibitors and beta blockers to manage heart disease
How It Is Treated With Stem Cell Therapy
One of the most effective treatments for muscular dystrophy is stem cell therapy.
Stem cells are being investigated as a potential source for regenerating, mending, and rebuilding muscle fibers and dead tissues.
Stem cells have the ability to divide and re-divide, causing the body to produce new cells.
The dead and damaged cells and tissues were either replaced or fixed and restored by these new cells.
The healing process is hastened and healthy muscle fibers are created when stem cells are injected into the body.
Muscle degeneration is also exacerbated by inflammation. Stem cells are anti-inflammatory cells that release anti-inflammatory chemicals to assist reduce inflammation.
Shifa Clinic offers cutting-edge regenerative medicine treatments that are an alternative to surgeries and transplants if you're looking for a certified and premier stem cell therapy facility in Pakistan.
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