Thalassemia Major: Available Treatment Options
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What is Thalassemia?
Hemoglobin is an iron-containing protein present inside the red blood cells that normally transports oxygen in the blood and delivers it to all the organs in the body. Thalassemia is a genetic defect involving this hemoglobin protein.
The inherited defect in the hemoglobin interferes with its oxygen-carrying capacity, thereby depriving all the organs including brain and heart from getting adequate oxygen, leading to brain disorders. In addition, this defect leaves the red blood cells more liable to destruction, thus decreasing the amount of healthy red blood cells and causing anemia, a type of blood disorder.
In case of Thalassemia minor, a mild form of Thalassemia you may not develop any symptoms, however in case of Thalassemia Major, a more severe form of Thalassemia you can develop problems such as easy fatigability, generalized weakness, and lethargy, a pale look and yellowish discoloration of the skin, distention of the abdomen as well as malformation of the facial bones.
History of disease in a family, cousin marriage and origin from certain ethnic descent are some of the commonly attributed factors to increase the risk of developing Thalassemia.
- Today cousin marriage is declared illegal in most of the developed world; however, it is a commonly practiced tradition especially in the developing countries. Whatever the case may, from a strictly medical point of view, this practice causes pooling of the defective genes in some families, thus increasing the risk of Thalassemia transmission.
- Thalassemia is more commonly found in people with the Middle Eastern, Asian and African Italian or Greek ethnic descent.
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Century Medical & Dental Center
260 Ave X,
Brooklyn, NY 11223
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